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New paradigm for drug toxicity screening efficent and ultimate therapy for diseases

Research papers

Introduces NEXEL’s Research papers

Title Impact Factor
Direct and Indirect Contribution of Human Embryonic Stem Cell‒Derived Hepatocyte‒Like cells to Liver Repair in Mice.(2012)
Gastroenterology, DOI: 10.1053/j.gastro.2011.11.030.
20.773
Phosphorylation of a Polycomb component of EZH2 by AKT activates STAT3 and promotes self‒renewal and tumorigenicity of glioblastoma stem‒like cells. (2013)
Cancer Cell, DOI: 10.1016/j.ccr.2013.04.008
22.844
Mitochondrial Induced and Self‒Monitored Intrinsic Apoptosis by Antitumor Theranostic Prodrug: In Vivo Imaging and Precise Cancer Treatment.(2014)
Journal of the American Chemical Society, DOI: 10.1021/ja510421q
14.357
Phosphodiesterase 9A Controls Nitric-oxide Independent cGMP and Hypertrophic Heart Disease.(2014)
Nature, DOI: 10.1038/nature14332
41.577
Regenerative medicine for the heart: perspectives on stem-cell therapy. (2014)
Antioxidants & Redox Signaling, DOI: 10.1089/ars.2014.6063.
6.53
Enhanced Metabolizing Activity of Human ES Cell‒Derived Hepatocytes Using a 3D Culture System with Repeated Exposures to Xenobiotics.(2015)
Toxicological Sciences, DOI: 10.1093/toxsci/kfv121
4.181
The Msi Family of RNA‒Binding Proteins Function Redundantly as Intestinal Oncoproteins.(2015)
Cell Reports, DOI: 10.1016/j.celrep.2015.11.022.
8.032
Functional Correction of Large Factor VIII Gene Chromosomal Inversions in Hemophilia A Patient‒Derived iPSCs Using CRISPR‒Cas9.(2015)
Cell Stem Cell, DOI: 10.1016/j.stem.2015.07.001.
23.29
Nanotopography Promotes Pancreatic Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells.(2016)
ACS nano, DOI: 10.1021/acsnano.5b06985.
13.709
Comparison of adult stem cells derived from multiple stem cell niches.(2016)
Biotechnology Letters, DOI: 10.1007/s10529-016-2050-2.
1.846
Functional Connection with Cardiac Tissues Confers Maturation Phenotypes in hPSC-Derived PHOX2B::GFP Expressing Sympathetic Neurons.(2016)
Cell stem cell, DOI: 10.1016/j.stem.2016.05.002
23.29
Milk Fat Globule‒EGF Factor8, secreted by Mesenchymal stem cells protects Against Liver Fibrosis in Mice. (2017)
Gastroenterology, DOI: 10.1053/j.gastro.2016.12.003.
20.773
Prediction of hepatotoxicity for drugs using human pluripotent stem cell-derived hepatocytes. (2017)
Cell Biology and Toxicology, DOI: 10.1007/s10565-017-9392-y
3.39
Using a neonatal rat system as a bioincubator to generate adult-like mature cardiomyocytes from human and mouse pluripotent stem cells. (2017)
Nature protocol, DOI: 10.1038/nprot.2017.089
12.423
Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy. (2017)
Cell Reports, DOI: 10.1016/j.celrep.2016.12.040
8.032
Current Understanding of Stem Cell and Secretome Therapies in Liver Diseases. (2017)
Tissue Eng Regen Med, DOI: 10.1007/s13770-017-0093-7
1.216
Rho-associated kinase inhibitor enhances the culture condition of isolated mouse salivary gland cells in vitro. (2018)
Tissue and Cell, DOI: 10.1016/j.tice.2018.07.002
1.553
Human induced pluripotent stemcell linewith cytochrome P450 enzyme polymorphism (CYP2C19*2/CYP3A5*3C) generated from lymphoblastoid cells. (2018)
Stem Cell Research, DOI:10.1016/j.scr.2017.12.014
3.929
Generation of cytochrome P450 polymorphic human induced pluripotent stem cell lines with defective CYP activities. (2018)
Stem Cell Research, DOI:10.1016/j.scr.2018.07.010
3.929
Prediction of hepatotoxicity for drugs using human pluripotent stem cell-derived hepatocytes. (2018)
Cell Biol Toxicol, DOI 10.1007/s10565-017-9392-y
5.097
Automated Dynamic Clamp for Simulation of IK1 in Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes in Real Time Using Patchliner Dynamite8. (2019)
Current Protocols in Pharmacology, DOI: 10.1002/cpph.70
1.000
Collagen Type I Containing Hybrid Hydrogel Enhances Cardiomyocyte Maturation in a 3D Cardiac Model. (2019)
MDPI polymers, Doi:10.3390/polym11040687
3.164
Synthetic probes for in vitro purification and in vivo tracking of hepatocytes derived from human pluripotent stem cells. (2019)
Biomaterials, DOI:10.1016/j.biomaterials.2019.119431
10.273
Modulating cardiomyocyte and fibroblast interaction using layer-by-layer deposition facilitates synchronisation of cardiac macro tissues. (2020)
Soft Matter, DOI: 10.1039/c9sm01531k
3.399
ER stress reliever enhances functionalities of in vitro cultured hepatocytes. (2020)
Stem Cell Research, DOI: 10.1016/j.scr.2020.101732
3.929
Milk Fat Globule-Epidermal Growth Factor VIII Ameliorates Brain Injury in the Subacute Phase of Cerebral Ischemia in an Animal Model. (2020)
The Korean Neurosurgical Society, DOI: 10.3340/jkns.2019.0188
1.187
Milk Fat Globule-EGF Factor 8 Contributes to Progression of Hepatocellular Carcinoma. (2020)
MDPI Cancers, DOI:10.3390/cancers12020403
6.162
Human Embryonic Stem Cell-Derived Wilson’s Disease Model for Screening Drug Efficacy. (2020)
MDPI Cells, DOI: 10.3390/cells9040872
5.656
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