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New paradigm for drug toxicity screening efficent and ultimate therapy for diseases

Research papers

Introduces NEXEL’s Research papers

Title Impact Factor
Direct and Indirect Contribution of Human Embryonic Stem Cell‒Derived Hepatocyte‒Like cells to Liver Repair in Mice.(2012)
Gastroenterology 142: 602‒611
Phosphorylation of a Polycomb component of EZH2 by AKT activates STAT3 and promotes self‒renewal and tumorigenicity of glioblastoma stem‒like cells. (2013)
Cancer Cell 23: 839‒852
Mitochondrial Induced and Self‒Monitored Intrinsic Apoptosis by Antitumor Theranostic Prodrug: In Vivo Imaging and Precise Cancer Treatment.(2014)
Journal of the American Chemical Society 136: 17836‒17843
Phosphodiesterase 9A Controls Nitric-oxide Independent cGMP and Hypertrophic Heart Disease.(2014)
Nature 519, 472-476
Regenerative medicine for the heart: perspectives on stem-cell therapy. (2014)
Antioxidants & Redox Signaling 21, 2018-2031
Enhanced Metabolizing Activity of Human ES Cell‒Derived Hepatocytes Using a 3D Culture System with Repeated Exposures to Xenobiotics.(2015)
Toxicological Sciences 147: 190‒206
The Msi Family of RNA‒Binding Proteins Function Redundantly as Intestinal Oncoproteins.(2015)
Cell Reports 13: 2440‒2455
Functional Correction of Large Factor VIII Gene Chromosomal Inversions in Hemophilia A Patient‒Derived iPSCs Using CRISPR‒Cas9.(2015)
Cell Stem Cell 17: 213‒220
Nanotopography Promotes Pancreatic Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells.(2016)
ACS nano 10: 3342‒3355
Comparison of adult stem cells derived from multiple stem cell niches.(2016)
Biotechnology Letters 38:751‒759
Functional Connection with Cardiac Tissues Confers Maturation Phenotypes in hPSC-Derived PHOX2B::GFP Expressing Sympathetic Neurons.(2016)
Cell stem cell, 19, 95-106
Milk Fat Globule‒EGF Factor8, secreted by Mesenchymal stem cells protects Against Liver Fibrosis in Mice. (2017)
Gastroenterology, 152:1174-1186
Prediction of hepatotoxicity for drugs using human pluripotent stem cell-derived hepatocytes. (2017)
Cell Biology and Toxicology (in press)
Using a neonatal rat system as a bioincubator to generate adult-like mature cardiomyocytes from human and mouse pluripotent stem cells.(2017)
Nature protocol 12:2097-2109
Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy.(2017)
Cell Reports, 18, 571-582
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