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私たちはヒト細胞を作り出しています

薬物毒性スクリーニング、疾病の効率的で究極の療法のための新しいパラダイム

研究報告

NEXELの研究報告

タイトル インパクト・ファクター
Direct and Indirect Contribution of Human Embryonic Stem Cell‒Derived Hepatocyte‒Like cells to Liver Repair in Mice.(2012)
Gastroenterology 142: 602‒611
20.773
Phosphorylation of a Polycomb component of EZH2 by AKT activates STAT3 and promotes self‒renewal and tumorigenicity of glioblastoma stem‒like cells. (2013)
Cancer Cell 23: 839‒852
22.844
Mitochondrial Induced and Self‒Monitored Intrinsic Apoptosis by Antitumor Theranostic Prodrug: In Vivo Imaging and Precise Cancer Treatment.(2014)
Journal of the American Chemical Society 136: 17836‒17843
14.357
Phosphodiesterase 9A Controls Nitric-oxide Independent cGMP and Hypertrophic Heart Disease.(2014)
Nature 519, 472-476
41.577
Regenerative medicine for the heart: perspectives on stem-cell therapy. (2014)
Antioxidants & Redox Signaling 21, 2018-2031
6.53
Enhanced Metabolizing Activity of Human ES Cell‒Derived Hepatocytes Using a 3D Culture System with Repeated Exposures to Xenobiotics.(2015)
Toxicological Sciences 147: 190‒206
4.181
The Msi Family of RNA‒Binding Proteins Function Redundantly as Intestinal Oncoproteins.(2015)
Cell Reports 13: 2440‒2455
8.032
Functional Correction of Large Factor VIII Gene Chromosomal Inversions in Hemophilia A Patient‒Derived iPSCs Using CRISPR‒Cas9.(2015)
Cell Stem Cell 17: 213‒220
23.29
Nanotopography Promotes Pancreatic Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells.(2016)
ACS nano 10: 3342‒3355
13.709
Comparison of adult stem cells derived from multiple stem cell niches.(2016)
Biotechnology Letters 38:751‒759
1.846
Functional Connection with Cardiac Tissues Confers Maturation Phenotypes in hPSC-Derived PHOX2B::GFP Expressing Sympathetic Neurons.(2016)
Cell stem cell, 19, 95-106
23.29
Milk Fat Globule‒EGF Factor8, secreted by Mesenchymal stem cells protects Against Liver Fibrosis in Mice. (2017)
Gastroenterology, 152:1174-1186
20.773
Prediction of hepatotoxicity for drugs using human pluripotent stem cell-derived hepatocytes. (2017)
Cell Biology and Toxicology (in press)
3.39
Using a neonatal rat system as a bioincubator to generate adult-like mature cardiomyocytes from human and mouse pluripotent stem cells.(2017)
Nature protocol 12:2097-2109
12.423
Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy.(2017)
Cell Reports, 18, 571-582
8.032
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