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Maturation step is performed through the provided media and can be used on the 10th day.
CYP induction rates depend on the induction method and exact isoform. CYP1A2 can usually be more readily detected whereas we recommend 3D-cultures to test other isoforms such as CYP3A4.
We do not have any validation data for liver metabolism assays.
Immature Hepatocytes (ALB positive),