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Calcium transient

Nautilai

Nautilai
  • Fluorescence-based assay
  • Calcium transient applications
  • Transient Amplitude, Frequency,Rise / Fall Rat
  • High-throughput
Application
  • Calcium channel assay
  • Early pipeline drug screening
  • Toxicity assessment

Key Endpoints

Amplitude

Rising
/ Falling Rate

Propagation

Fluorescence (Intensity)

“Visualizing Cellular Calcium Signals– Nautilai Calcium transient Service”

NeXST provides a service that utilizes the Curibio Nautilai platform to precisely measure calcium transients (Ca²⁺ transients) in iPSC-derived cardiomyocytes. Calcium transients are key indicators closely linked to cardiomyocyte contraction and relaxation, offering a more intuitive understanding of drug-induced cellular responses and electrophysiological characteristics.

·Key Advantages
1. High-resolution, real-time Ca²⁺ signal detection enabling high-throughput analysis
2. Cost-effective accessibility, as experiments can be conducted using standard culture plates
3. Comprehensive cardiac physiological data for safety and efficacy evaluation through analysis of calcium dynamics under drug treatment
4. AI/ML-enabled integration, supporting connectivity with Curi Bio’s cloud-based platform for faster and more efficient analysis

Through Nautilai, NeXST delivers cardiac safety assessments that go beyond electrical signals, providing insights more directly reflective of cardiomyocyte function.

Beyond conventional boundaries,
we deliver a bold new paradigm.